ru·in·a·tion /ˌruəˈneʃən/
  毀滅;滅亡;禍根
  Ru·in·a·tion n.  The act of ruining, or the state of being ruined.
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  ruination
       n 1: an irrecoverable state of devastation and destruction; "you
            have brought ruin on this entire family" [syn: ruin]
       2: an event that results in destruction [syn: ruin]
       3: failure that results in a loss of position or reputation
          [syn: downfall, ruin]
       4: destruction achieved by wrecking something [syn: laying
          waste, ruin, ruining, wrecking]